Intravenous Tissue Plasminogen Activator Can Be Safely Given without Complete Blood Count Results Back

Intravenous Tissue Plasminogen Activator Can Be Safely Given without Complete Blood Count Results Back

INTRODUCTION It is well known that the efficacy of intravenous (i.v.) tissue plasminogen activator (tPA) is time-dependent when used to treat patients with acute ischemic strokes. AIM Our study examines the safety issue of giving IV tPA without complete blood count (CBC) resulted. MATERIALS AND METHODS This is a retrospective observational study by examining the database from Huashan Hospit...

Defining intravenous recombinant tissue plasminogen activator failure.

Administering Intravenous Alteplase (Tissue Plasminogen Activator [tPA])

Step 1: Eligibility-The eligibility criteria for patients with acute ischemic stroke within 3 hours of symptom onset include: • An adult (> 18 years of age) • Exclusion of intrancranial hemorrhage by an imaging technique sensitive for the presence of hemorrhage • Arrives at the emergency department in time to be treated within 3 hours of symptom onset • The recommended dose of IV tPA is 0.9 mg/...

Tobramycin and gentamicin can safely be given by slow push.

Sir, We read with great interest the letter by Nix and Matthias 1 regarding pharmacokinetic considerations relating to tigecycline use in urinary tract infections (UTIs). We agree with the authors that tige-cycline should not be used for UTIs when other therapies including aminoglycosides, carbapenems and colistin are options; however, in rare situations, tigecycline may be considered. In a rec...

In-hospital stroke treated with intravenous tissue plasminogen activator.

BACKGROUND AND PURPOSE In-hospital strokes (IHSs) are potential candidates for thrombolysis. We analyzed the treatment procedures, safety, and efficacy of intravenous tissue plasminogen activator (IV-tPA) in IHSs compared with out-of-hospital strokes (OHSs). METHODS This study was based on a multicenter prospective registry of patients treated with IV-tPA divided into IHSs and OHSs. We record...